Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
VC_1462RstB2 protein; Similar to GP:2564358; identified by sequence similarity; putative. (127 aa)    
Predicted Functional Partners:
VC_1463
RstA2 protein; Similar to GP:2564352; identified by sequence similarity; putative.
     
 0.806
zot
Zona occludens toxin; Increases the permeability of the small intestine mucosa by affecting the structure of intercellular tight junctions (zonula occludens).
     
 0.568
VC_1464
Transcriptional repressor RstR; Similar to GP:2564351; identified by sequence similarity; putative.
     
 0.544
VC_1460
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.531
VC_1454
RstA1 protein; Similar to GP:2564352; identified by sequence similarity; putative.
     
 0.525
cep
Colonization factor; Similar to; identified by sequence similarity; putative.
       0.489
ace
Accessory cholera enterotoxin; Increases short-circuit current in rabbit ileal tissue mounted in Ussing chambers, by increasing the potential difference. Cultures of V.cholerae containing the cloned ace gene cause fluid secretion in ligated rabbit ileal loops.
       0.486
VC_1084
Sensory box sensor histidine kinase; Similar to PID:1773367; identified by sequence similarity; putative.
      
 0.466
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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