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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1494Aminopeptidase N; Similar to GB:M15273 SP:P04825 GB:M15676 GB:X04020 PID:147142; identified by sequence similarity; putative. (868 aa)    
Predicted Functional Partners:
VC_A0644
NADH oxidase, putative; Similar to GB:AE000782; identified by sequence similarity; putative.
    
 0.761
VC_1993
2,4-dienoyl-CoA reductase; Similar to SP:P42593 PID:606019 GB:U00096 PID:1789463; identified by sequence similarity; putative.
   
 
 0.731
VC_A0513
Amino acid biosynthesis aminotransferase; Similar to PID:1806263; identified by sequence similarity; putative.
   
 0.708
VC_1493
Hypothetical protein; Identified by Glimmer2; putative.
       0.706
pepB
Peptidase B; Probably plays an important role in intracellular peptide degradation.
  
 0.704
pepA
Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity).
  
 0.704
glyA1
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.687
glyA2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.687
VC_2279
Aminoacyl-histidine dipeptidase; Similar to GB:M34034 SP:P15288 GB:X14790 PID:1208983 PID:147140; identified by sequence similarity; putative.
     
 0.660
gshB
Glutathione synthetase; Similar to SP:P04425 GB:X01666 PID:41625 PID:882476 GB:U00096; identified by sequence similarity; putative.
    
 0.653
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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