Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_1521Sensor histidine kinase; Similar to GB:L13078 SP:Q06067 PID:290419 GB:U00096 PID:1736874; identified by sequence similarity; putative. (677 aa)    
Predicted Functional Partners:
VC_1522
Sigma-54 dependent response regulator; Similar to SP:P14375 GB:M28369 PID:396343 PID:1790437; identified by sequence similarity; putative.
 
 
 0.933
VC_1523
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
     0.859
VC_1524
ABC transporter, permease protein; Similar to GB:AE000666; identified by sequence similarity; putative.
 
     0.847
VC_1525
ABC transporter, ATP-binding protein; Similar to GB:AE000782; identified by sequence similarity; putative.
 
     0.810
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
 
     0.784
VC_1527
Molybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
     0.728
VC_1516
Iron-sulfur cluster-binding protein; Similar to GB:X61204 PID:44800 PID:1747410; identified by sequence similarity; putative.
  
     0.715
VC_1511
Formate dehydrogenase, cytochrome B556 subunit; Similar to GB:AE000657; identified by sequence similarity; putative.
  
     0.680
VC_1515
Chaperone, formate dehydrogenase-specific, putative; Similar to GP:3327032; identified by sequence similarity; putative.
  
     0.657
VC_1349
Sensory box sensor histidine kinase/response regulator; Similar to PID:1653075; identified by sequence similarity; putative.
 
 
0.646
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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