STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1554Glycerophosphoryl diester phosphodiesterase, putative; Similar to SP:P54527 PID:1303930 GB:AL009126; identified by sequence similarity; putative. (237 aa)    
Predicted Functional Partners:
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
  
 0.840
ugpE
Glycerol-3-phosphate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
 
  
 0.784
VC_1550
Glycerol-3-phosphate ABC transporter, permease protein; Similar to SP:P10905 GB:U00039 PID:43247 PID:466588 GB:U00096; identified by sequence similarity; putative.
 
  
 0.781
VC_1553
Glycerol-3-phosphate regulon repressor; Similar to SP:P09392 GB:M96795 PID:146186 PID:606358 GB:U00096; identified by sequence similarity; putative.
 
   
 0.779
VC_A0747
Anaerobic glycerol-3-phosphate dehydrogenase, subunit A; Similar to GB:M20938 SP:P13032 PID:146177 GB:U00096 PID:1788574; identified by sequence similarity; putative.
 
 0.776
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 
  
 0.773
VC_A0136
Glycerophosphoryl diester phosphodiesterase; Similar to SP:P09394 GB:X56907 GB:Y00536 PID:41581 PID:902489; identified by sequence similarity; putative.
  
  
0.746
ugpC
Glycerol-3-phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family.
 
  
 0.718
VC_1549
Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein; Similar to SP:P10904 GB:U00039 GB:M33735 PID:43244 PID:466589; identified by sequence similarity; putative.
 
  
 0.673
VC_0135
Lysophospholipase L2; Similar to PID:1449198; identified by sequence similarity; putative.
    
 0.634
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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