STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1562Beta-lactamase-related protein; Similar to GB:M19530 SP:P04190 SP:P14488 PID:143128; identified by sequence similarity; putative. (390 aa)    
Predicted Functional Partners:
VC_A0644
NADH oxidase, putative; Similar to GB:AE000782; identified by sequence similarity; putative.
  
 0.925
thiI
Thiamin biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 0.867
VC_1561
Transcriptional regulator, LysR family; Similar to SP:P10183 PID:150233; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
  
 0.769
VC_A1078
Transcriptional regulator, LuxR family; Similar to PID:887806 GB:U00096 SP:Q46791 PID:1789219; identified by sequence similarity; putative.
    
 
 0.726
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
 
 0.705
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
   
 
 0.704
rsmH
Conserved hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
   
   0.693
VC_A0643
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 0.688
VC_1563
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
     
 0.682
VC_A1053
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 0.671
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.