STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1580Transcriptional regulator, LysR family; Similar to GB:X66866 PID:403331 SP:P52692; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family. (303 aa)    
Predicted Functional Partners:
VC_1582
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0753 family.
 
     0.893
VC_1581
NADH dehydrogenase, putative; Similar to SP:P33607 PID:397909 GB:U00096 PID:1788614 PID:1799638; identified by sequence similarity; putative.
 
   
 0.801
VC_1947
Transcriptional regulator, LysR family; Similar to GB:L42023 SP:P43011 PID:1007393 PID:1221499 PID:1139588; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.605
VC_1577
Hypothetical protein; Identified by Glimmer2; putative.
       0.588
VC_1578
Hypothetical protein; Identified by Glimmer2; putative.
       0.588
VC_1579
Enterobactin synthetase component F-related protein; Similar to GB:M60177 SP:P11454 GB:M17354 PID:145843 PID:551801; identified by sequence similarity; putative.
       0.588
VC_1390
Transcriptional regulator, LysR family; Similar to PID:1493807; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
   
 0.547
VC_2103
Transcriptional regulator, LysR family; Similar to GB:X73124 SP:P39592 PID:413948 GB:AL009126; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
   
 0.532
VC_1049
Transcriptional regulator, LysR family; Similar to GP:1139588; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
   
 0.526
irgB
Iron-regulated virulence regulatory protein IrgB; Transcription activation of the irgA gene. In the presence of sufficient iron, transcription of both irgA and irgB is negatively regulated by a fur-like protein. In low iron conditions, negative regulation of transcription is removed, and production of irgB leads to positive transcriptional activation of irgA (By similarity).
  
   
 0.517
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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