Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_1584ankB protein; Similar to PID:563740 PID:1754534; identified by sequence similarity; putative. (188 aa)    
Predicted Functional Partners:
VC_1636
Helicase-related protein; Similar to SP:P36927 GB:U00096; identified by sequence similarity; putative.
  
 0.903
VC_A0067
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.892
apaH
Bis(5`-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
   
 0.881
VC_1585
Catalase; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.
 
 0.873
VC_2042
Histone deacetylase/AcuC/AphA family protein; Similar to SP:P28606 PID:580726 PID:669044 PID:669045; identified by sequence similarity; putative.
   
 0.860
VC_0353
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
 0.827
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.827
VC_1764
Hypothetical protein; Identified by Glimmer2; putative.
    
 0.827
VC_1543
Hypothetical protein; Identified by Glimmer2; putative.
 
 0.817
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.815
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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