STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1588Transcriptional regulator, LysR family; Similar to PID:727227 SP:P52666; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family. (293 aa)    
Predicted Functional Partners:
irgB
Iron-regulated virulence regulatory protein IrgB; Transcription activation of the irgA gene. In the presence of sufficient iron, transcription of both irgA and irgB is negatively regulated by a fur-like protein. In low iron conditions, negative regulation of transcription is removed, and production of irgB leads to positive transcriptional activation of irgA (By similarity).
  
   
 0.771
VC_1390
Transcriptional regulator, LysR family; Similar to PID:1493807; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.760
VC_1589
Alpha-acetolactate decarboxylase; Converts acetolactate into acetoin.
     
 0.759
VC_2324
Transcriptional regulator, LysR family; Similar to SP:P32484 PID:405876 PID:466777 GB:U00096 PID:1788481; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.752
VC_0787
Transcriptional regulator, LysR family; Similar to SP:P46068 PID:1050466 GB:U00096 PID:1788706 PID:1799763; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.751
VC_A0889
Transcriptional regulator, LysR family; Similar to PID:924993 SP:P52689; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.750
VC_A0542
Transcriptional regulator, LysR family; Similar to SP:P32484 PID:405876 PID:466777 GB:U00096 PID:1788481; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.742
VC_A0635
Transcriptional regulator, LysR family; Similar to GB:U00096 PID:1788100; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.732
VC_A0876
D-serine deaminase activator; Similar to SP:P46068 PID:1050466 GB:U00096 PID:1788706 PID:1799763; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.730
VC_A1055
Transcriptional regulator, LysR family; Similar to PID:1652750; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.693
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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