STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1598ABC transporter, periplasmic substrate-binding protein-related protein; Similar to GB:L42023 PID:1006358 PID:1221197 PID:1205330 SP:P45024; identified by sequence similarity; putative. (274 aa)    
Predicted Functional Partners:
VC_1603
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.763
VC_A0583
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.757
VC_1601
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.751
VC_1528
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.708
VC_1529
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.685
VC_1651
Response regulator VieB; Similar to GP:3123892; identified by sequence similarity; putative.
  
 
   0.647
VC_A0211
Sensory box sensor histidine kinase; Similar to PID:561864; identified by sequence similarity; putative.
  
     0.647
VC_A0210
Response regulator, putative; Phosphodiesterase (PDE) that catalyzes the hydrolysis of 3'3'-cyclic GMP-AMP (3'3'-cGAMP), leading to linear 5'-pApG. Counteracts the function of the 3'3'-cGAMP synthase DncV, and is involved in the modulation of intracellular 3'3'-cGAMP levels. Enhances bacterial chemotaxis and inhibits intestinal colonization in vivo. Thus exerts a crucial role in regulating bacterial infectivity through catalyzing 3'3'-cGAMP degradation. Is specific for 3'3'-cGAMP since it cannot degrade other cGAMP linkage isomers (3'2'-, 2'3'-, and 2'2'-cGAMPs). Is also able to hydrol [...]
 
     0.642
VC_A0980
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.623
VC_A0189
Response regulator; Similar to PID:1736859 PID:1736868; identified by sequence similarity; putative.
  
 
   0.588
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.