Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_1621Agglutination protein; Similar to GB:M64540 PID:150976; identified by sequence similarity; putative. (445 aa)    
Predicted Functional Partners:
VC_0165
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.972
VC_0913
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.970
VC_1674
Periplasmic linker protein, putative; Similar to GP:2605916; identified by sequence similarity; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.969
VC_1675
Multidrug resistance protein, putative; Similar to GB:L11616 PID:438853 SP:P52477; identified by sequence similarity; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.968
VC_1756
Periplasmic linker protein, putative; Similar to GP:2605916; identified by sequence similarity; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.967
VC_0628
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.963
VC_A0639
AcrA/AcrE family protein; Similar to GB:AE000657; identified by sequence similarity; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.963
VC_1565
Outer membrane protein TolC, putative; Similar to SP:P02930 GB:X54049 PID:43101 PID:43107 PID:882565; identified by sequence similarity; putative.
  
  
 0.933
VC_A1080
Secretion protein, HlyD family; Similar to GP:1314576; identified by sequence similarity; putative.
 
 
 0.933
tolC
Outer membrane protein TolC; Outer membrane channel, which is required for the function of several efflux systems (By similarity). Required to export RtxA cytotoxin; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
  
  
0.931
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.