Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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gene co-occurrence
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VC_1624Conserved hypothetical protein; Involved in norspermidine biosynthesis. Catalyzes the synthesis of carboxynorspermidine from L-aspartate 4-semialdehyde and 1,3-diaminopropane. Is also active with putrescine as a substrate. Essential for biofilm formation; Belongs to the saccharopine dehydrogenase family. carboxynorspermidine synthase subfamily. (414 aa)    
Predicted Functional Partners:
nspC
Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine. Essential for biofilm formation.
 
 
 0.997
VC_A0814
Agmatinase; Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466; identified by sequence similarity; putative; Belongs to the arginase family.
   
 0.944
VC_A1063
Ornithine decarboxylase, inducible; Similar to GB:M64495 SP:P24169 PID:147331 GB:U00096 PID:1651300; identified by sequence similarity; putative.
    
 0.907
speG
Spermidine n1-acetyltransferase; Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine. It can use polyamines such as spermine and N(1)-acetylspermine, but not putrescine or cadaverine; Belongs to the acetyltransferase family.
   
 
  0.902
folE
GTP cyclohydrolase; Similar to GB:U00007 SP:P27511 GB:X63910 PID:312964 PID:405902; identified by sequence similarity; putative.
    
   0.712
VC_1293
Aspartate aminotransferase; Similar to SP:P00509 GB:X03629 GB:X05904 PID:41011 PID:41013; identified by sequence similarity; putative.
      
 0.541
VC_0775
Vibriobactin synthesis protein, putative; Similar to GB:M60177 SP:P11454 GB:M17354 PID:145843 PID:551801; identified by sequence similarity; putative.
  
  
 0.476
VC_2364
Aspartokinase I/homoserine dehydrogenase, threonine-sensitive; Similar to SP:P27725; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
  
 0.443
VC_2684
Aspartokinase II/homoserine dehydrogenase, methionine-sensitive; Similar to GB:L19201 SP:P00562 GB:J01651 GB:V00305 PID:146841; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
  
 0.443
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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