Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_1649Trypsin, putative; Similar to SP:P26262 PID:200359; identified by sequence similarity; putative. (548 aa)    
Predicted Functional Partners:
VC_1584
ankB protein; Similar to PID:563740 PID:1754534; identified by sequence similarity; putative.
    
 0.759
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.742
VC_1636
Helicase-related protein; Similar to SP:P36927 GB:U00096; identified by sequence similarity; putative.
    
 0.731
VC_2042
Histone deacetylase/AcuC/AphA family protein; Similar to SP:P28606 PID:580726 PID:669044 PID:669045; identified by sequence similarity; putative.
    
  0.724
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
   0.719
VC_0566
Protease DO; Similar to GB:M36536 SP:P09376 GB:M29955 GB:X12457 PID:146414; identified by sequence similarity; putative; Belongs to the peptidase S1C family.
  
 
 
 0.715
dnaJ
dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
    
  0.695
VC_A0788
DnaJ-related protein; Similar to SP:P48207 PID:893246; identified by sequence similarity; putative.
    
  0.695
VC_0353
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.686
VC_1070
Phosphatase, putative; Similar to PID:2224838; identified by sequence similarity; putative.
  
 
 0.686
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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