STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1671Cystathionine beta-lyase; Similar to GB:M12858 SP:P06721 PID:146824 PID:882537 PID:1789383; identified by sequence similarity; putative. (396 aa)    
Predicted Functional Partners:
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity).
  
 
 0.972
VC_0968
Cysteine synthase A; Similar to GB:M21451 SP:P11096 GB:X12615 PID:145686 PID:41201; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.947
VC_2364
Aspartokinase I/homoserine dehydrogenase, threonine-sensitive; Similar to SP:P27725; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.941
VC_2684
Aspartokinase II/homoserine dehydrogenase, methionine-sensitive; Similar to GB:L19201 SP:P00562 GB:J01651 GB:V00305 PID:146841; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.941
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.930
VC_0537
Cysteine synthase B; Similar to SP:P29848 GB:X52093 GB:X59595 PID:581757; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.927
VC_1061
Cysteine synthase/cystathionine beta-synthase family protein; Similar to GB:AL123456; identified by sequence similarity; putative.
  
 0.919
VC_A0620
Thiosulfate sulfurtransferase SseA, putative; Similar to SP:P31142 GB:U00096 PID:1788869 PID:1799924; identified by sequence similarity; putative.
 
 
 0.905
VC_2685
5,10-methylenetetrahydrofolate reductase; Similar to GB:L19201 SP:P00394 GB:V01502 PID:305044 PID:42000; identified by sequence similarity; putative; Belongs to the methylenetetrahydrofolate reductase family.
 
 0.882
VC_A0644
NADH oxidase, putative; Similar to GB:AE000782; identified by sequence similarity; putative.
    
 0.857
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.