Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_1672DNA-3-methyladenine glycosidase I; Similar to SP:P05100 GB:J02606 GB:X03845 PID:147920 PID:43030; identified by sequence similarity; putative. (193 aa)    
Predicted Functional Partners:
VC_A1017
methylated-DNA--protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
   
 0.786
VC_1674
Periplasmic linker protein, putative; Similar to GP:2605916; identified by sequence similarity; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.749
VC_1675
Multidrug resistance protein, putative; Similar to GB:L11616 PID:438853 SP:P52477; identified by sequence similarity; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.749
VC_1676
Phage shock protein C; Similar to SP:P23855 GB:X57560 PID:42541 GB:U00096 PID:1742136; identified by sequence similarity; putative.
       0.649
VC_1678
Phage shock protein A; Similar to SP:P23853 GB:X57560 PID:42539 GB:U00096 PID:1742134; identified by sequence similarity; putative.
       0.645
VC_1673
Transporter, AcrB/D/F family; Similar to GB:AE000657; identified by sequence similarity; putative; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.610
VC_A1018
Ada regulatory protein; Similar to SP:Q10630 PID:1340083 PID:1513196 GB:AL123456; identified by sequence similarity; putative.
 
   
 0.564
VC_1677
Phage shock protein B; Similar to SP:P23854 GB:X57560 PID:42540 GB:U00096 PID:1742135; identified by sequence similarity; putative.
       0.480
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
    0.453
VC_2364
Aspartokinase I/homoserine dehydrogenase, threonine-sensitive; Similar to SP:P27725; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
    0.428
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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