STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_1690Similar to GP:3237318; identified by sequence similarity; putative. (374 aa)    
Predicted Functional Partners:
VC_1689
Hypothetical protein; Identified by Glimmer2; putative.
      0.949
VC_A0655
Sucrose-6-phosphate dehydrogenase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
  
 0.936
VC_1594
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
 
 
 0.929
VC_0613
beta-N-acetylhexosaminidase; Similar to PID:1698442; identified by sequence similarity; putative.
     
 0.902
VC_2217
beta-N-acetylhexosaminidase; Similar to PID:1698442; identified by sequence similarity; putative.
     
 0.902
nanH
Neuraminidase; Cleaves the terminal sialic acid (N-acetyl neuraminic acid) from carbohydrate chains in glycoproteins providing free sialic acid which can be used as carbon and energy sources. Sialidases have been suggested to be pathogenic factors in microbial infections. Facilitates cholera toxin binding to host intestinal epithelial cells by converting cell surface polysialogangliosides to GM1 monogangliosides; Belongs to the glycosyl hydrolase 33 family.
     
  0.900
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.787
VC_1691
Hypothetical protein; Identified by Glimmer2; putative.
       0.559
VC_0132
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.532
VC_A0860
Alpha-amylase; Similar to SP:P25718 GB:X58994 PID:41966 PID:466709 GB:U00096; identified by sequence similarity; putative.
 
  
 0.522
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.