STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1698Conserved hypothetical protein; Identified by Glimmer2; putative. (215 aa)    
Predicted Functional Partners:
VC_1697
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.849
VC_1696
DNA-binding protein inhibitor Id-2-related protein; Similar to SP:P41136 PID:1030074; identified by sequence similarity; putative.
       0.737
VC_A0102
CbbY family protein; Similar to GB:U00096 PID:1789046; identified by sequence similarity; putative.
  
  
 0.660
VC_A0662
CbbY family protein; Similar to GB:U00096 PID:1789046; identified by sequence similarity; putative.
  
  
 0.660
VC_1699
Hypothetical protein; Identified by Glimmer2; putative.
       0.497
cgtA
GTP1/Obg family protein; Depletion experiments lead to gene down regulation and a dramatic increase in ppGpp levels, like those seen in the stringent response. There is no change in cell morphology in depletion experiments , but cells are very sensitive to the DNA-damaging agent hydroxyurea and are very elongated. Overexpression reduces growth and leads to elongated cells. Overexpression of proteins with C-terminal deletions of 29 or 62 amino acids showed fewer elongated cells. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
 
 
    0.492
VC_0302
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
    0.468
VC_1695
Formate transporter 1, putative; Similar to SP:P21501 PID:147154 GB:U00096 PID:1651428 PID:1651435; identified by sequence similarity; putative.
       0.434
uppP
Undecaprenol kinase, putative; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
  
    0.430
zapB
Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
   
    0.405
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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