Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_1723Conserved hypothetical protein; Identified by Glimmer2; putative. (229 aa)    
Predicted Functional Partners:
VC_2638
Pyridine nucleotide-disulfide oxidoreductase, class I; Similar to GB:AL009126; identified by sequence similarity; putative.
   
 0.934
VC_0186
Glutathione reductase; Similar to SP:P06715 GB:M13141 PID:146248 PID:466637 GB:U00096; identified by sequence similarity; putative.
    
 0.921
lpd
Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
    
 0.918
sthA
Pyridine nucleotide-disulfide oxidoreductase, class I; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
    
 0.896
VC_1724
Hypothetical protein; Identified by Glimmer2; putative.
       0.799
VC_2378
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
     0.713
VC_1664
ABC transporter, periplasmic substrate-binding protein, putative; Similar to GB:U00096 PID:1788051; identified by sequence similarity; putative.
 
  
 0.690
VC_1722
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.674
VC_1534
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
    0.636
VC_1667
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
     0.594
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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