Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_1745Succinate-semialdehyde dehydrogenase; Similar to GB:M88334 SP:P25526 PID:147901 GB:U00096 PID:1789015; identified by sequence similarity; putative; Belongs to the aldehyde dehydrogenase family. (488 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
 
 0.931
VC_2089
Succinate dehydrogenase, flavoprotein subunit; Similar to GB:J01619 SP:P10444 GB:X00980 PID:146199 PID:42925; identified by sequence similarity; putative; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
   
 0.925
VC_2656
Fumarate reductase, flavoprotein subunit; Similar to GB:U14003 SP:P00363 GB:J01611 PID:145263 PID:536998; identified by sequence similarity; putative.
   
 0.925
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.924
VC_2088
Succinate dehydrogenase, iron-sulfur protein; Similar to PID:2239250; identified by sequence similarity; putative; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
   
 
 0.904
VC_2090
Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
   
 
 0.904
VC_2091
Succinate dehydrogenase, cytochrome b556 subunit; Similar to GB:J01619 SP:P10446 GB:X00980 PID:146197 PID:42923; identified by sequence similarity; putative.
   
 
 0.904
VC_2657
Fumarate reductase, iron-sulfur protein; Similar to GB:U14003 SP:P00364 GB:J01611 PID:145264 PID:536997; identified by sequence similarity; putative; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
   
 
 0.904
frdC
Fumarate reductase, 15 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
     
  0.900
frdD
Fumarate reductase, 13 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
     
  0.900
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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