Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nanKROK family protein; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. (287 aa)    
Predicted Functional Partners:
nanE
Conserved hypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
 0.999
VC_1776
N-acetylneuraminate lyase, putative; Similar to GB:L42023 SP:P44539 PID:1003186 PID:1222055 PID:1204400; identified by sequence similarity; putative; Belongs to the DapA family.
 
 
 0.974
VC_1783
N-acetylglucosamine-6-phosphate deacetylase; Similar to SP:O32445; identified by sequence similarity; putative.
 
  
 0.873
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
 
   
 0.855
murP
PTS system, sucrose-specific IIBC component, putative; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
  
 
 0.839
VC_0910
PTS system, trehalose-specific IIBC component; Similar to SP:P36672 GB:U06195 PID:459401 GB:U00096 PID:2367362; identified by sequence similarity; putative.
  
 
 0.839
VC_0995
PTS system, N-acetylglucosamine-specific IIABC component; Similar to GP:2541900; identified by sequence similarity; putative.
  
 
 0.839
VC_2013
PTS system, glucose-specific IIBC component; Similar to GB:J02618 SP:P05053 PID:147393 GB:U00096 PID:1651541; identified by sequence similarity; putative.
  
 
 0.839
VC_A0653
PTS system, sucrose-specific IIBC component; Similar to GB:M76768 SP:P22825 PID:155262; identified by sequence similarity; putative.
  
 
 0.839
VC_0395
UTP--glucose-1-phosphate uridylyltransferase; Similar to GB:U03751 PID:432985 SP:Q59633 PID:1345068; identified by sequence similarity; putative.
    
 0.815
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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