STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (353 aa)    
Predicted Functional Partners:
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
 0.999
VC_2422
Nicotinate-nucleotide pyrophosphorylase, carboxylating; Similar to GB:L20833 SP:P30011 GB:L28105 PID:310262 PID:456041; identified by sequence similarity; putative; Belongs to the NadC/ModD family.
 
 
 0.997
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
     
 0.648
VC_2089
Succinate dehydrogenase, flavoprotein subunit; Similar to GB:J01619 SP:P10444 GB:X00980 PID:146199 PID:42925; identified by sequence similarity; putative; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
  
 0.641
VC_2656
Fumarate reductase, flavoprotein subunit; Similar to GB:U14003 SP:P00363 GB:J01611 PID:145263 PID:536998; identified by sequence similarity; putative.
 
  
 0.638
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.638
VC_0919
Serine acetyltransferase-related protein; Similar to GB: GB: GB: PID:1107505 PID:1184048; identified by sequence similarity; putative.
  
    0.629
VC_0923
Serine acetyltransferase-related protein; Similar to GB:AE000511 SP:P71405 PID:1518452 PID:2314370; identified by sequence similarity; putative.
  
    0.629
VC_2649
Serine acetyltransferase; Similar to SP:P05796 GB:M15745 GB:M34333 PID:145676 PID:145694; identified by sequence similarity; putative.
  
    0.629
iscS
Aminotransferase NifS, class V; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
  
 0.566
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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