STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1869Pyruvate formate-lyase 1 activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (246 aa)    
Predicted Functional Partners:
VC_1866
Formate acetyltransferase; Similar to GB:X08035 SP:P09373 PID:42370 GB:U00096 PID:1651427; identified by sequence similarity; putative.
  
 0.982
VC_2033
Alcohol dehydrogenase/acetaldehyde dehydrogenase; Similar to GB:M33504 SP:P17547 GB:X59263 GB:X67326 PID:145206; identified by sequence similarity; putative; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
 
 0.908
pta
Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.785
grcA
Formate acetyl transferase-related protein; Acts as a radical domain for damaged PFL and possibly other radical proteins.
  
   
 0.777
VC_1870
Hypothetical protein; Identified by Glimmer2; putative.
       0.763
VC_1871
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0304 family.
       0.678
VC_1868
Methyl-accepting chemotaxis protein; Similar to PID:1066851; identified by sequence similarity; putative.
       0.661
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
     
 0.660
VC_0250
Iron-containing alcohol dehydrogenase family protein RfbM; Similar to GB:M26941 SP:P13604 PID:144714; identified by sequence similarity; putative.
 
  
 0.649
VC_1147
Iron-containing alcohol dehydrogenase; Similar to SP:P10127 PID:1150583 PID:1322937 PID:3337; identified by sequence similarity; putative.
 
  
 0.578
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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