Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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VC_1876Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0434 family. (59 aa)    
Predicted Functional Partners:
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
  
  
 0.924
lpxK
Tetraacyldisaccharide 4`-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
     0.871
msbA
Transport ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
       0.849
VC_1879
Rec2-related protein; Similar to GB:L42023 SP:P44408 PID:1003026 PID:1221968 PID:1204319; identified by sequence similarity; putative.
       0.807
VC_1880
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.731
VC_1700
Intracellular sepatation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
  
     0.517
VC_1897
Hit family protein; Similar to GB:U00096 PID:1787346; identified by sequence similarity; putative.
  
    0.503
VC_2235
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 
   0.471
VC_2075
Histidine triad family protein; Similar to GB:Pyro_h; identified by sequence similarity; putative.
  
    0.445
prmB
Adenine-specific methylase, putative; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
  
 
 0.421
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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