Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_1888Hemolysin-related protein; Similar to SP:P09545 GB:M36855 GB:X51746 PID:1136779 PID:155182; identified by sequence similarity; putative. (691 aa)    
Predicted Functional Partners:
VC_A0027
Chitinase; Similar to SP:P32823 PID:216207; identified by sequence similarity; putative.
  
 
 0.788
VC_A0700
Chitodextrinase; Similar to GP:3928775; identified by sequence similarity; putative.
  
 
 0.763
VC_0934
Capsular polysaccharide biosynthesis glycosyltransferase, putative; Similar to GB:U00096 SP:P71241 PID:1407618 PID:1736749 PID:1736753; identified by sequence similarity; putative.
   
    0.730
VC_0306
Thioredoxin; Similar to SP:P00274 GB:M87049 GB:K02845 GB:M10424 GB:M12779; identified by sequence similarity; putative; Belongs to the thioredoxin family.
    
   0.648
VC_0977
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
   0.648
VC_A0752
Thioredoxin 2; Similar to SP:P33636 GB:U00096 PID:1788936 PID:1799987; identified by sequence similarity; putative.
    
   0.648
VC_1952
Chitinase; Similar to GP:3851166; identified by sequence similarity; putative.
  
   0.534
VC_1548
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.530
VC_1073
Chitinase, putative; Similar to PID:1698444; identified by sequence similarity; putative.
   
 
 0.514
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
  
  
 0.496
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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