STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1888Hemolysin-related protein; Similar to SP:P09545 GB:M36855 GB:X51746 PID:1136779 PID:155182; identified by sequence similarity; putative. (691 aa)    
Predicted Functional Partners:
VC_1548
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.828
VC_0414
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.758
rtxA
RTX toxin RtxA; [Multifunctional-autoprocessing repeats-in-toxin]: Precursor of a multifunctional toxin that causes destruction of the actin cytoskeleton by covalent cross-linking of actin and inactivation of Rho GTPases when translocated into the host cytoplasm. Upon translocation into the host cell, undergoes autoprocessing in cis mediated by the peptidase C80 domain (also named CPD domain): the protease activity is activated upon binding inositol hexakisphosphate (InsP6) present at the host cell membrane and delivers the Cysteine protease domain-containing toxin F3 chain to the host [...]
  
 
 0.670
VC_A0849
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.644
VC_0934
Capsular polysaccharide biosynthesis glycosyltransferase, putative; Similar to GB:U00096 SP:P71241 PID:1407618 PID:1736749 PID:1736753; identified by sequence similarity; putative.
   
    0.634
VC_A0107
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.487
VC_1889
Ribosomal-protein-serine acetyltransferase, putative; Similar to SP:P13857 GB:X15860 PID:42749 GB:U00096 PID:1742324; identified by sequence similarity; putative.
 
     0.477
VC_2385
RNA-directed DNA polymerase; Similar to GB:Z12832 PID:42501; identified by sequence similarity; putative.
  
    0.473
VC_A0108
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.454
VC_A0110
Hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.442
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.