Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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fadRFatty acid metabolism regulator protein; Multifunctional regulator of fatty acid metabolism. (279 aa)    
Predicted Functional Partners:
plsB
Glycerol-3-phosphate acyltransferase; Similar to GP:147295; identified by sequence similarity; putative; Belongs to the GPAT/DAPAT family.
  
   
 0.817
proQ
Conserved hypothetical protein; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.
  
   
 0.783
fabA
3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length (By similarity).
      
 0.781
metJ
Met repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
   
 0.768
VC_2040
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0352 family.
  
     0.765
seqA
seqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.761
rraB
Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.729
VC_0152
Transcriptional regulator, TetR family; Similar to GB:U00096 PID:1790401; identified by sequence similarity; putative.
  
  
 0.727
VC_0648
Conserved hypothetical protein; May be involved in cell division.
  
     0.722
bamC
Lipoprotein-34 NlpB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.713
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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