Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
VC_1949pvcA protein; Similar to GP:3212172; identified by sequence similarity; putative. (608 aa)    
Predicted Functional Partners:
VC_1944
PvcB protein; Similar to GP:3212173; identified by sequence similarity; putative.
 
  
 0.873
VC_1948
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
VC_2087
2-oxoglutarate dehydrogenase, E1 component; Similar to GB:J01619 SP:P07015 PID:146201 PID:43019 GB:U00096; identified by sequence similarity; putative.
   
 
 0.642
VC_1945
FAD monooxygenase, PheA/TfdB family; Similar to SP:P15245 PID:170525; identified by sequence similarity; putative.
 
     0.578
hmp
Ferrisiderophore reductase; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). Belongs to the globin family. Two-domain flavohemoproteins subfamily.
  
     0.528
VC_1947
Transcriptional regulator, LysR family; Similar to GB:L42023 SP:P43011 PID:1007393 PID:1221499 PID:1139588; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
       0.519
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
    
   0.511
VC_1369
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.494
VC_0775
Vibriobactin synthesis protein, putative; Similar to GB:M60177 SP:P11454 GB:M17354 PID:145843 PID:551801; identified by sequence similarity; putative.
  
  
 0.484
VC_A0812
Leucine aminopeptidase-related protein; Similar to PID:1694931; identified by sequence similarity; putative.
  
     0.456
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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