Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_1977Aspartate aminotransferase, putative; Similar to GB:U00096 PID:1788627 PID:1799660; identified by sequence similarity; putative. (404 aa)    
Predicted Functional Partners:
VC_A0513
Amino acid biosynthesis aminotransferase; Similar to PID:1806263; identified by sequence similarity; putative.
   
 0.930
VC_0392
Aminotransferase, class V; Similar to SP:P31030 PID:164759; identified by sequence similarity; putative.
  
 0.929
VC_1492
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.929
ilvD
Dihydroxy-acid dehydratase; Similar to GP:288532; identified by sequence similarity; putative; Belongs to the IlvD/Edd family.
  
 
 0.927
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
  
 
 0.927
argA
N-acetylglutamate synthase; Similar to SP:P08205 GB:Y00492 PID:581038 PID:882710 GB:U00096; identified by sequence similarity; putative.
  
 
 0.926
ilvE
Branched-chain amino acid amiotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.925
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.920
VC_1905
Alanine dehydrogenase; Similar to GP:3220269; identified by sequence similarity; putative; Belongs to the AlaDH/PNT family.
     
 0.916
VC_0019
Valine-pyruvate aminotransferase; Similar to SP:P09053 PID:466710 GB:U00096 PID:1789996; identified by sequence similarity; putative.
     
 0.912
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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