STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_1983Peptidase, putative; Similar to SP:P47788 PID:1871406 PID:565284; identified by sequence similarity; putative. (615 aa)    
Predicted Functional Partners:
VC_2126
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
    
   0.793
VC_A0065
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.747
lifO
Lipase activator protein, putative; May be involved in the folding of the extracellular lipase during its passage through the periplasm; Belongs to the lipase chaperone family.
  
     0.727
vcc
Collagenase; Possesses gelatinolytic activity; Belongs to the peptidase M9A family.
  
    0.681
VC_A0218
Thermolabile hemolysin; Similar to GB:M36437 SP:Q99289 PID:155178; identified by sequence similarity; putative.
  
     0.678
VC_0764
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.630
volA
Lipase, putative; Required for the utilization of the prevalent host lipid lysophosphatidylcholine (LPC). Functions as a lipase that cleaves exogenous LPC and generates free fatty acids, which are then transported into the cell by fatty acid transporters such as FadL, and used in various metabolic pathways.
 
 
   0.629
prtV
Protease; Metalloprotease that exhibits a cytotoxic effect leading to cell death. In host tissues, it could play a role in pathogenesis by modulating the stability of the extracellular matrix components such as fibronectin and fibrinogen. Also able to cleave plasminogen.
  
    0.627
VC_A0064
TonB system receptor, putative; Similar to GB:L27149 PID:529727; identified by sequence similarity; putative.
  
     0.626
VC_A0085
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.611
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.