Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
VC_1989Conserved hypothetical protein; Identified by Glimmer2; putative. (237 aa)    
Predicted Functional Partners:
VC_0343
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.979
birA
birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
    0.920
VC_1990
ATP-dependent helicase, DinG family; Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110; identified by sequence similarity; putative.
  
  
 0.853
tsaC
Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
 
  
 0.820
VC_1987
Outer membrane lipoprotein Slp, putative; Similar to GB:U00096 PID:1736439 PID:1736445 PID:1788108; identified by sequence similarity; putative.
  
  
 0.784
VC_1986
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
    0.770
VC_1988
Hypothetical protein; Identified by Glimmer2; putative.
       0.770
tadA
yfhC protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.713
VC_1985
long-chain-fatty-acid--CoA ligase; Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096; identified by sequence similarity; putative.
       0.677
rnd
Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.
  
    0.636
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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