Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VC_2070Phosphohistidine phosphatase; Similar to GB:U00096 PID:1788681; identified by sequence similarity; putative. (157 aa)    
Predicted Functional Partners:
VC_2072
Peptidase, insulinase family; Similar to SP:P35559 PID:56492; identified by sequence similarity; putative; Belongs to the peptidase M16 family.
       0.740
flhA
Flagellar biosynthetic protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
       0.677
fliA
RNA polymerase sigma factor for flagellar operon FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
       0.653
VC_2067
MinD-related protein; Similar to GP:3695013; identified by sequence similarity; putative.
       0.653
VC_2068
Flagellar biosynthetic protein FlhF, putative; Similar to SP:Q01960 GB:X66445 PID:39919 GB:AL009126; identified by sequence similarity; putative.
       0.653
VC_2065
Chemotaxis protein CheY; Similar to GB:X61231 PID:45323 SP:Q51455; identified by sequence similarity; putative.
       0.643
VC_2060
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
     0.622
VC_2063
Chemotaxis protein CheA; Similar to GB:M34669 SP:P07363 PID:145529 PID:145530 GB:U00096; identified by sequence similarity; putative.
       0.614
VC_2064
Chemotaxis protein CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
       0.614
VC_2061
ParA family protein; Similar to GP:3721574; identified by sequence similarity; putative.
       0.605
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.