Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
VC_2097Esterase/lipase YbfF, putative; Similar to GB:U00096 PID:1786902; identified by sequence similarity; putative. (257 aa)    
Predicted Functional Partners:
seqA
seqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
       0.749
VC_1740
Oxidoreductase, acyl-CoA dehydrogenase family; Similar to GP:4902957; identified by sequence similarity; putative.
   
 0.747
VC_2231
Oxidoreductase, acyl-CoA dehydrogenase family; Similar to PID:1208978 PID:984577 GB:U00096 SP:Q47146 PID:1552791; identified by sequence similarity; putative.
   
 0.747
VC_2098
Hypothetical protein; Identified by Glimmer2; putative.
       0.741
VC_2095
Phosphoglucomutase; Similar to SP:P36938 GB:U08369 PID:473888 GB:U00096 PID:1651293; identified by sequence similarity; putative.
   
 
 0.737
apaH
Bis(5`-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
  0.734
VC_2099
Flavodoxin 1; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
     
 0.702
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.695
VC_1584
ankB protein; Similar to PID:563740 PID:1754534; identified by sequence similarity; putative.
  
 0.641
VC_0248
Acyl carrier protein, putative; Similar to GB:X59554 PID:48390; identified by sequence similarity; putative.
   
 
 0.639
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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