STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_2135Sigma-54 dependent response regulator; Similar to PID:2352978; identified by sequence similarity; putative. (479 aa)    
Predicted Functional Partners:
VC_2136
Sensory box sensor histidine kinase; Similar to PID:2338728; identified by sequence similarity; putative.
 0.952
VC_0303
Sensor histidine kinase; Similar to GP:2808665; identified by sequence similarity; putative.
  
 0.900
VC_2748
Nitrogen regulation protein; Similar to SP:P19906 PID:155172; identified by sequence similarity; putative.
 0.890
VC_2453
Sensor histidine kinase/response regulator; Similar to GB:D10888 SP:P26607 PID:216535 PID:882680 GB:U00096; identified by sequence similarity; putative.
  
 0.886
VC_2529
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.881
VC_1349
Sensory box sensor histidine kinase/response regulator; Similar to PID:1653075; identified by sequence similarity; putative.
  
0.880
VC_2369
Sensor histidine kinase FexB; Similar to SP:P22763 GB:X53315 PID:40951 PID:606149 GB:U00096; identified by sequence similarity; putative.
  
 0.880
VC_1653
Sensory box sensor histidine kinase/response regulator VieS; Similar to GP:3123890; identified by sequence similarity; putative.
  
 0.866
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
    
 0.863
VC_2131
Flagellar assembly protein FliH, putative; Similar to GB:M62408 SP:P15934 GB:X52093 PID:154028; identified by sequence similarity; putative.
 
 
 0.857
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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