close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliDFlagellar hook-associated protein FliD; Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity). (666 aa)    
Predicted Functional Partners:
fliS
Flagellar protein FliS; Similar to GB:U12816 PID:1254205; identified by sequence similarity; putative.
 
 
 0.999
VC_2190
Flagellar hook-associated protein FlgL; Similar to PID:2443634; identified by sequence similarity; putative.
 
 
 0.991
VC_2191
Flagellar hook-associated protein FlgM; Similar to PID:2443633; identified by sequence similarity; putative.
 
  
 0.990
flaG
Flagellin FlaG; Similar to PID:2271029; identified by sequence similarity; putative; To FlaG in other Vibrio species.
 
  
 0.989
VC_2133
Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
 
  
 0.983
fliE
Flagellar hook-basal body complex protein FliE; Similar to PID:2338730; identified by sequence similarity; putative.
 
  
 0.983
VC_2197
Flagellar hook protein FlgE; Similar to GB:X51737 SP:P16322 GB:X52093 PID:47673; identified by sequence similarity; putative.
 
  
 0.980
VC_2198
Basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.980
VC_2130
Flagellum-specific ATP synthase FliI; Similar to PID:1071643 SP:P52612 GB:U00096 PID:1736607 PID:1788251; identified by sequence similarity; putative.
 
  
 0.977
VC_2126
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
  
 0.976
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.