Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
flaGFlagellin FlaG; Similar to PID:2271029; identified by sequence similarity; putative; To FlaG in other Vibrio species. (153 aa)    
Predicted Functional Partners:
fliD
Flagellar hook-associated protein FliD; Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
 
  
 0.989
fliS
Flagellar protein FliS; Similar to GB:U12816 PID:1254205; identified by sequence similarity; putative.
 
  
 0.987
flaB
Flagellin FlaB; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. FlaB is not essential for flagellar synthesis and motility (By similarity).
  
 
 0.922
VC_2126
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
  
 0.905
fliE
Flagellar hook-basal body complex protein FliE; Similar to PID:2338730; identified by sequence similarity; putative.
 
  
 0.896
VC_2190
Flagellar hook-associated protein FlgL; Similar to PID:2443634; identified by sequence similarity; putative.
 
 
 0.884
flaE
Flagellin FlaE; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. FlaE is not essential for flagellar synthesis and motility.
  
 
 0.882
flaD
Flagellin FlaD; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. FlaD is not essential for flagellar synthesis and motility.
  
 
 0.880
VC_2271
Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.880
flaC
Flagellin FlaC; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. FlaC is not essential for flagellar synthesis and motility (By similarity).
  
 
 0.827
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.