STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flaGFlagellin FlaG; Similar to PID:2271029; identified by sequence similarity; putative; To FlaG in other Vibrio species. (153 aa)    
Predicted Functional Partners:
fliD
Flagellar hook-associated protein FliD; Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
 
  
 0.989
fliS
Flagellar protein FliS; Similar to GB:U12816 PID:1254205; identified by sequence similarity; putative.
 
  
 0.987
flaB
Flagellin FlaB; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. FlaB is not essential for flagellar synthesis and motility (By similarity).
  
 
 0.928
VC_2271
Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.896
flaE
Flagellin FlaE; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. FlaE is not essential for flagellar synthesis and motility.
  
 
 0.888
VC_2126
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
  
 0.886
VC_2190
Flagellar hook-associated protein FlgL; Similar to PID:2443634; identified by sequence similarity; putative.
 
 
 0.880
flaD
Flagellin FlaD; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. FlaD is not essential for flagellar synthesis and motility.
  
 
 0.878
VC_2063
Chemotaxis protein CheA; Similar to GB:M34669 SP:P07363 PID:145529 PID:145530 GB:U00096; identified by sequence similarity; putative.
  
 
 0.869
flaA
Flagellin core protein A; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. FlaA is required to form a core or scaffold into which the other flagellins are inserted to provide structural integrity. Essential for flagellar synthesis and motility; important for full virulence.
  
 
 0.841
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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