STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_2204Negative regulator of flagellin synthesis FlgM, putative; Similar to GB:L14437 SP:P39809 PID:451869 PID:1762336 GB:AL009126; identified by sequence similarity; putative. (107 aa)    
Predicted Functional Partners:
fliA
RNA polymerase sigma factor for flagellar operon FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
  
 0.985
fliS
Flagellar protein FliS; Similar to GB:U12816 PID:1254205; identified by sequence similarity; putative.
  
 
 0.982
VC_2205
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.978
VC_2203
Flagellar protein, putative; Similar to PID:1272364; identified by sequence similarity; putative.
 
  
 0.940
fliD
Flagellar hook-associated protein FliD; Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
 
  
 0.924
VC_2191
Flagellar hook-associated protein FlgM; Similar to PID:2443633; identified by sequence similarity; putative.
 
  
 0.923
VC_2200
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
  
 0.912
VC_2198
Basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.904
VC_2199
Flagellar basal-body rod protein FlgC; Similar to GB:U00096 SP:P75935 PID:1787314; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
  
  
 0.891
VC_2127
Flagellar protein FliL, putative; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
  
 0.889
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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