Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
viuBVibriobactin utilization protein ViuB; Involved in intracellular removal of iron from iron- vibriobactin complex. Vibriobactin is an iron-chelating compound involved in the transport of iron from the bacterial environment into the cell cytoplasm (By similarity); Belongs to the SIP oxidoreductase family. (271 aa)    
Predicted Functional Partners:
vibB
Vibriobactin-specific isochorismatase; Involved in the biosynthesis of the catechol siderophore vibriobactin. Vibriobactin is a chelating compound involved in transporting iron from the bacterial environment into the cell cytoplasm; Belongs to the isochorismatase family.
 
  
 0.944
vibE
Vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase; Activation of the carboxylate group of 2,3-dihydroxy-benzoate (DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate, preparing that molecule for the final stages of vibriobactin synthesis.
 
  
 0.864
VC_0775
Vibriobactin synthesis protein, putative; Similar to GB:M60177 SP:P11454 GB:M17354 PID:145843 PID:551801; identified by sequence similarity; putative.
 
  
 0.804
viuA
Ferric vibriobactin receptor; Receptor for ferric vibriobactin; Belongs to the TonB-dependent receptor family.
 
  
 0.762
VC_1446
Toxin secretion transporter, putative; Similar to SP:P16532 GB:M24197 PID:150495 PID:150514; identified by sequence similarity; putative.
   
   0.730
VC_1448
RTX toxin transporter; Similar to GP:4455067; identified by sequence similarity; putative.
   
   0.730
VC_A1084
Toxin secretion ATP-binding protein; Similar to GB:L12145 GB:X68815 GB:X80055 SP:Q04473 PID:38959; identified by sequence similarity; putative.
   
   0.730
VC_0199
Hemolysin secretion ATP-binding protein, putative; Similar to GB:L42023 PID:1006302 PID:1221167 PID:1205301 SP:Q57180; identified by sequence similarity; putative.
  
 
 0.702
VC_1499
ABC transporter, ATP-binding protein; Similar to SP:P45861 PID:853754 GB:AL009126; identified by sequence similarity; putative.
  
 
 0.702
msbA
Transport ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
  
 
 0.702
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.