STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
copACation transport ATPase, E1-E2 family; Involved in copper export. (915 aa)    
Predicted Functional Partners:
VC_2216
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.828
VC_A0530
Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative.
  
  
 0.624
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
       0.567
VC_1583
Superoxide dismutase, Cu-Zn; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
    
 0.535
VC_1068
Transcriptional regulator, ArsR family; Similar to SP:P15905 GB:X16045 PID:42717; identified by sequence similarity; putative.
 
  
 0.495
VC_1409
Multidrug resistance protein, putative; Similar to GP:3378279; identified by sequence similarity; putative.
  
  
 0.488
VC_2271
Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.483
hlyU
Transcriptional activator HlyU; Up-regulates the expression of the hemolysin gene, hlyA, and may promote expression of other virulence determinants in vivo. It may have both positive and negative regulator activities.
 
  
 0.480
VC_A0642
Transcriptional regulator, ArsR family; Similar to GB:X66866 PID:403332 SP:P52695; identified by sequence similarity; putative.
 
  
 0.472
VC_1607
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.462
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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