STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmhA-2Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (191 aa)    
Predicted Functional Partners:
gmhB
Histidinol phosphatase-related protein; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position in vitro. Also catalyzes the dephosphorylation of D-glycero-alpha-D-manno-heptose-1,7- bisphosphate in vitro; Belongs to the GmhB family.
 
 0.994
hisB
Imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase; Similar to SP:P06987 GB:X03416 PID:41696 PID:41711 GB:U00096; identified by sequence similarity; putative; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
  
 
 0.844
dnaA
Chromosomal DNA replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).
    
 
 0.822
hldD
ADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
 
  
 0.768
VC_0236
ADP-heptose--LPS heptosyltransferase II; Similar to PID:1916630; identified by sequence similarity; putative.
 
  
 0.735
VC_0225
Lipopolysaccharide biosynthesis protein, putative; Similar to GB:L42023 PID:1003419 PID:1222185 PID:1204517 PID:1573227; identified by sequence similarity; putative.
 
  
 0.687
VC_2131
Flagellar assembly protein FliH, putative; Similar to GB:M62408 SP:P15934 GB:X52093 PID:154028; identified by sequence similarity; putative.
   
   0.681
VC_0223
ADP-heptose--LPS heptosyltransferase II, putative; Similar to GB:L42023 SP:P44011 PID:1003930 PID:1222457 PID:1204774; identified by sequence similarity; putative.
 
  
 0.655
VC_A0189
Response regulator; Similar to PID:1736859 PID:1736868; identified by sequence similarity; putative.
    
 
 0.643
VC_1083
Hypothetical protein; Identified by Glimmer2; putative.
    
 
 0.641
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.