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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_2255Phosphatidate cytidylyltransferase; Similar to GB:L42023 SP:P44937 PID:1006039 PID:1221024 PID:1205166; identified by sequence similarity; putative; Belongs to the CDS family. (280 aa)    
Predicted Functional Partners:
uppS
Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
  
  
 0.986
VC_1215
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Similar to GB:M12299 SP:P06978 PID:473749 GB:U00096 PID:1736571; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.899
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
  
  
 0.887
VC_2253
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the peptidase M50B family.
  
    0.864
VC_2513
1-acyl-sn-glycerol-3-phosphate acyltransferase; Similar to GB:M68936 SP:P26974 PID:154236; identified by sequence similarity; putative; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
    
 0.832
VC_1935
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase-related protein; Similar to GB:U00096 PID:1787676; identified by sequence similarity; putative.
    
 0.825
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.824
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.790
lpxD
UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
     
 0.738
VC_A0714
Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
    
 0.676
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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