Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bolAbolA protein; Transcriptional regulator that plays an important role in general stress response. (106 aa)    
Predicted Functional Partners:
VC_2044
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.935
nfuA
Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.815
rlmG
Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
     
 0.803
VC_2298
Lipoprotein, putative; Similar to GB:L42023 SP:P43782 PID:1003225 PID:1222077 PID:644853; identified by sequence similarity; putative.
       0.755
VC_2299
Peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
       0.755
VC_2300
ampG protein, putative; Similar to GB:U00096 SP:P36670 PID:1773117 PID:1786636 PID:563855; identified by sequence similarity; putative.
       0.694
VC_0139
DPS family protein; Similar to GB:L42023 SP:P45173 PID:1007363 PID:1221482 PID:1205585; identified by sequence similarity; putative; Belongs to the Dps family.
   
  
 0.654
atpB
ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
    
 
 0.613
grx
Glutaredoxin 1; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity).
  
 
 0.585
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
    
 
 0.555
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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