STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_2300ampG protein, putative; Similar to GB:U00096 SP:P36670 PID:1773117 PID:1786636 PID:563855; identified by sequence similarity; putative. (462 aa)    
Predicted Functional Partners:
vibE
Vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase; Activation of the carboxylate group of 2,3-dihydroxy-benzoate (DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate, preparing that molecule for the final stages of vibriobactin synthesis.
  
  
 0.668
vibC
Vibriobactin-specific isochorismate synthase; Similar to PID:2182763; identified by sequence similarity; putative; Belongs to the isochorismate synthase family.
  
  
 0.636
menF
Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
  
  
 0.636
rlmG
Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
  
    0.633
VC_2299
Peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
    0.627
VC_2298
Lipoprotein, putative; Similar to GB:L42023 SP:P43782 PID:1003225 PID:1222077 PID:644853; identified by sequence similarity; putative.
       0.624
VC_0696
Chorismate mutase/prephenate dehydrogenase; Similar to SP:Q02287 GB:M74135 GB:X60420 PID:415010 PID:43345; identified by sequence similarity; putative.
 
  
 0.602
VC_0705
Chorismate mutase/prephenate dehydratase; Similar to GB:L42023 SP:P43900 PID:1006481 PID:1221267 PID:1205390; identified by sequence similarity; putative.
  
 
 0.556
VC_1304
Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.542
bolA
bolA protein; Transcriptional regulator that plays an important role in general stress response.
     
 0.511
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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