STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_2323Conserved hypothetical protein; Identified by Glimmer2; putative. (322 aa)    
Predicted Functional Partners:
VC_2324
Transcriptional regulator, LysR family; Similar to SP:P32484 PID:405876 PID:466777 GB:U00096 PID:1788481; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
 
   
 0.818
gltS
Sodium/glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
  
    0.712
recC
Exodeoxyribonuclease V, 125 kDa subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and [...]
       0.495
VC_0170
Peptide ABC transporter, ATP-binding protein; Similar to GB:U00096 PID:1787051; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
  
    0.461
VC_0286
Gluconate permease, putative; Similar to PID:882633 GB:U00096 PID:1789097; identified by sequence similarity; putative.
  
   
 0.457
VC_A0517
1-phosphofructokinase; Similar to SP:P23539 GB:X53948 PID:405894 PID:41487 GB:U00096; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
   
    0.455
VC_2326
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.446
VC_2321
Hypothetical protein; Identified by Glimmer2; putative.
       0.427
VC_2098
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.414
hutX
Conserved hypothetical protein; Binds heme. Heme is transferred to the heme-degrading enzyme HutZ via a specific protein- protein interaction.
  
     0.406
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.