Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
VC_2395Hypothetical protein; Identified by Glimmer2; putative. (157 aa)    
Predicted Functional Partners:
VC_0371
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
 
   0.912
VC_1857
Primosomal replication protein N``; Similar to GB:D13958 PID:912452 GB:U00096 PID:1773149 PID:1786673; identified by sequence similarity; putative.
  
     0.722
VC_2298
Lipoprotein, putative; Similar to GB:L42023 SP:P43782 PID:1003225 PID:1222077 PID:644853; identified by sequence similarity; putative.
  
     0.698
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
       0.650
VC_1246
Hypothetical protein; Identified by Glimmer2; putative.
  
   
 0.631
VC_1895
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.624
VC_2392
Mutator MutT protein; Similar to GB:D10483 SP:P08337 GB:M20791 GB:X04831 PID:147795; identified by sequence similarity; putative; Belongs to the Nudix hydrolase family.
       0.597
VC_0030
Acetolactate synthase II, small subunit; Similar to GB:M87049 SP:P13048 GB:X02413 GB:X04890 PID:146459; identified by sequence similarity; putative.
  
     0.584
priB
Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
  
     0.551
VC_1893
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.544
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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