STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_2415Pyruvate dehydrogenase complex repressor; Similar to PID:455922 GB:U00096 SP:P06957 PID:1786303 PID:434009; identified by sequence similarity; putative. (256 aa)    
Predicted Functional Partners:
VC_A0924
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
  0.789
vibB
Vibriobactin-specific isochorismatase; Involved in the biosynthesis of the catechol siderophore vibriobactin. Vibriobactin is a chelating compound involved in transporting iron from the bacterial environment into the cell cytoplasm; Belongs to the isochorismatase family.
    
   0.763
VC_2414
Pyruvate dehydrogenase, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
 0.700
VC_2413
Pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
 0.676
VC_1335
Transcriptional regulator, GntR family; Similar to GB:U00096 PID:1787821; identified by sequence similarity; putative.
 
  
 0.669
VC_A0983
L-lactate permease, putative; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.659
lldD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
 
  
 0.607
VC_A0600
Repressor protein PhnR, putative; Similar to GP:1763080; identified by sequence similarity; putative.
  
  
 0.508
fadR
Fatty acid metabolism regulator protein; Multifunctional regulator of fatty acid metabolism.
  
   
 0.495
VC_1206
Histidine utilization repressor; Similar to GB:M33922 SP:P22773 PID:151276; identified by sequence similarity; putative.
  
  
 0.494
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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