Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
VC_2423Fimbrial protein; Similar to GB:M24281 SP:P08015 SP:P17837 GB:M14850 PID:151463; identified by sequence similarity; putative; Belongs to the N-Me-Phe pilin family. (167 aa)    
Predicted Functional Partners:
pilC
Type IV pilin biogenesis protein PilC; Involved in the translocation of the type IV pilin; Belongs to the GSP F family.
 
   
 0.935
VC_2424
Type IV pilus assembly protein PilB; Similar to GP:3220230; identified by sequence similarity; putative.
 
  
 0.930
VC_2426
Leader peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.898
VC_2630
Fimbrial assembly protein; Similar to GB:L13865 SP:P34750 PID:459551; identified by sequence similarity; putative.
 
   
 0.801
VC_0462
Twitching motility protein PilT; Similar to SP:P24559 GB:X67095 PID:151490; identified by sequence similarity; putative.
 
   
 0.786
tcpJ
Leader peptidase TcpJ; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. Processes the TcpA pilin precursor during membrane translocation.
 
   
 0.770
coaE
Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.726
VC_2422
Nicotinate-nucleotide pyrophosphorylase, carboxylating; Similar to GB:L20833 SP:P30011 GB:L28105 PID:310262 PID:456041; identified by sequence similarity; putative; Belongs to the NadC/ModD family.
  
  
 0.713
VC_2634
Fimbrial assembly protein PilM, putative; Similar to GB:L28837 PID:895925; identified by sequence similarity; putative.
 
   
 0.704
zapD
Conserved hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
       0.698
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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