STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_2423Fimbrial protein; Similar to GB:M24281 SP:P08015 SP:P17837 GB:M14850 PID:151463; identified by sequence similarity; putative; Belongs to the N-Me-Phe pilin family. (167 aa)    
Predicted Functional Partners:
VC_2424
Type IV pilus assembly protein PilB; Similar to GP:3220230; identified by sequence similarity; putative.
 
  
 0.933
pilC
Type IV pilin biogenesis protein PilC; Involved in the translocation of the type IV pilin; Belongs to the GSP F family.
 
   
 0.898
VC_2426
Leader peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.878
VC_2634
Fimbrial assembly protein PilM, putative; Similar to GB:L28837 PID:895925; identified by sequence similarity; putative.
 
   
 0.774
VC_0462
Twitching motility protein PilT; Similar to SP:P24559 GB:X67095 PID:151490; identified by sequence similarity; putative.
 
   
 0.756
VC_0857
Fimbrial assembly protein PilE, putative; Similar to GB:U02552 PID:1246304 PID:435924; identified by sequence similarity; putative.
 
  
0.744
tcpJ
Leader peptidase TcpJ; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. Processes the TcpA pilin precursor during membrane translocation.
 
   
 0.722
VC_2630
Fimbrial assembly protein; Similar to GB:L13865 SP:P34750 PID:459551; identified by sequence similarity; putative.
 
   
 0.715
VC_0408
MSHA pilin protein MshB; Similar to GB:X77217 PID:496758; identified by sequence similarity; putative.
   
 0.698
epsG
General secretion pathway protein G; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. Required for secretion of cholera toxin through the outer membrane.
   
 0.659
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.