Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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cpdACyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (272 aa)    
Predicted Functional Partners:
VC_2432
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.941
VC_0899
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
  0.905
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.905
VC_1126
Adenylosuccinate lyase; Similar to GB:M74924 SP:P25739 PID:145203 PID:42585 GB:U00096; identified by sequence similarity; putative; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.905
nutA
UDP-sugar hydrolase; Degradation of extracellular 5'-nucleotides for nutritional needs.
   
 
 0.904
VC_A0545
5`-nucleotidase, putative; Similar to GB:AE000520; identified by sequence similarity; putative; Belongs to the 5'-nucleotidase family.
   
 
 0.904
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.902
surE
Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
VC_2450
mazG protein; Similar to GB:J04039 SP:P33646 PID:416198 PID:882675 GB:U00096; identified by sequence similarity; putative.
    
  0.900
VC_2435
MutT/nudix family protein; Similar to SP:P36651 PID:882564 GB:U00096 PID:1789412; identified by sequence similarity; putative.
 
   
 0.874
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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