Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VC_2434Conserved hypothetical protein; Identified by Glimmer2; putative. (148 aa)    
Predicted Functional Partners:
VC_2435
MutT/nudix family protein; Similar to SP:P36651 PID:882564 GB:U00096 PID:1789412; identified by sequence similarity; putative.
 
  
 0.949
cpdA
Cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 0.860
VC_2432
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
     0.838
parC
Topoisomerase IV, subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
       0.662
parE
Topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
       0.662
zipA
Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
     0.586
tolC
Outer membrane protein TolC; Outer membrane channel, which is required for the function of several efflux systems (By similarity). Required to export RtxA cytotoxin; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
       0.557
VC_1002
dedD protein; Similar to GB:M68934 SP:P09549 PID:146366 GB:U00096 PID:1788653; identified by sequence similarity; putative.
  
     0.521
VC_2443
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
    0.521
VC_1841
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.467
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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