Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
VC_2443Conserved hypothetical protein; Identified by Glimmer2; putative. (202 aa)    
Predicted Functional Partners:
VC_2442
Pho4 family protein; Similar to GB:L42023 SP:P45268 PID:1007859 PID:1221747 PID:1205836; identified by sequence similarity; putative.
       0.711
VC_2441
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.643
VC_2547
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
     0.619
VC_2440
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.596
VC_2434
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
    0.521
VC_2466
sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...]
  
  
 0.513
VC_1379
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.441
slmA
Transcriptional regulator, TetR family; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
  
     0.439
VC_0957
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.430
VC_0268
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.428
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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