| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VC_0451 | VC_2472 | VC_0451 | VC_2472 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.644 |
| VC_0451 | erpA | VC_0451 | VC_0627 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | hesB family protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.456 |
| VC_0750 | VC_2472 | VC_0750 | VC_2472 | hesB family protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.793 |
| VC_0750 | nfuA | VC_0750 | VC_2720 | hesB family protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.768 |
| VC_1003 | VC_2119 | VC_1003 | VC_2119 | Bacteriocin production protein; Similar to GB:J01666 SP:P08550 PID:146367 PID:147415 GB:U00096; identified by sequence similarity; putative. | Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0115 family. | 0.426 |
| VC_1003 | VC_2472 | VC_1003 | VC_2472 | Bacteriocin production protein; Similar to GB:J01666 SP:P08550 PID:146367 PID:147415 GB:U00096; identified by sequence similarity; putative. | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.574 |
| VC_1003 | bamD | VC_1003 | VC_0708 | Bacteriocin production protein; Similar to GB:J01666 SP:P08550 PID:146367 PID:147415 GB:U00096; identified by sequence similarity; putative. | Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.465 |
| VC_2119 | VC_1003 | VC_2119 | VC_1003 | Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0115 family. | Bacteriocin production protein; Similar to GB:J01666 SP:P08550 PID:146367 PID:147415 GB:U00096; identified by sequence similarity; putative. | 0.426 |
| VC_2119 | VC_2472 | VC_2119 | VC_2472 | Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0115 family. | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.518 |
| VC_2470 | VC_2472 | VC_2470 | VC_2472 | Hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.587 |
| VC_2470 | sdhE | VC_2470 | VC_2471 | Hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well. | 0.815 |
| VC_2472 | VC_0451 | VC_2472 | VC_0451 | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.644 |
| VC_2472 | VC_0750 | VC_2472 | VC_0750 | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | hesB family protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.793 |
| VC_2472 | VC_1003 | VC_2472 | VC_1003 | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | Bacteriocin production protein; Similar to GB:J01666 SP:P08550 PID:146367 PID:147415 GB:U00096; identified by sequence similarity; putative. | 0.574 |
| VC_2472 | VC_2119 | VC_2472 | VC_2119 | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0115 family. | 0.518 |
| VC_2472 | VC_2470 | VC_2472 | VC_2470 | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | Hypothetical protein; Identified by Glimmer2; putative. | 0.587 |
| VC_2472 | bamD | VC_2472 | VC_0708 | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.533 |
| VC_2472 | cysQ | VC_2472 | VC_2722 | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | cysQ protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.485 |
| VC_2472 | erpA | VC_2472 | VC_0627 | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | hesB family protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.852 |
| VC_2472 | nfuA | VC_2472 | VC_2720 | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.810 |
