STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VC_2485Transcriptional regulator, LysR family; Similar to GB:D10483 SP:P10151 GB:M21150 PID:1128961 PID:146605; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family. (321 aa)    
Predicted Functional Partners:
rpoS
RNA polymerase sigma-38 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response (By similarity). May be required for the persistence of V.cholerae in aquatic habitats.
    
 
 0.750
VC_2486
Hypothetical protein; Identified by Glimmer2; putative.
       0.732
VC_2484
long-chain-fatty-acid--CoA ligase, putative; Similar to GB:L42023 SP:P44446 PID:1004105 PID:1221904 PID:1204261; identified by sequence similarity; putative.
       0.709
VC_2487
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.697
VC_2488
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.697
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 
 0.619
VC_1390
Transcriptional regulator, LysR family; Similar to PID:1493807; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.615
VC_1947
Transcriptional regulator, LysR family; Similar to GB:L42023 SP:P43011 PID:1007393 PID:1221499 PID:1139588; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
  
     0.588
VC_0152
Transcriptional regulator, TetR family; Similar to GB:U00096 PID:1790401; identified by sequence similarity; putative.
    
 
 0.586
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
    
 
 0.578
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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