STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (334 aa)    
Predicted Functional Partners:
arcA
Arginine deiminase; Similar to GB:X14694 SP:P13981 GB:S43866 PID:45286; identified by sequence similarity; putative.
 
 
 0.997
argG
Argininosuccinate synthase; Similar to GB:AL009126; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.996
carB
Carbamoyl-phosphate synthase, large subunit; Similar to GB:D10483 SP:P00968 GB:J01597 GB:V01500 PID:145464; identified by sequence similarity; putative.
 
 
 0.977
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.974
argA
N-acetylglutamate synthase; Similar to SP:P08205 GB:Y00492 PID:581038 PID:882710 GB:U00096; identified by sequence similarity; putative.
  
 
 0.966
argH
Argininosuccinate lyase; Similar to SP:P11447 GB:J01590 GB:M21446 PID:145335 PID:396307; identified by sequence similarity; putative.
  
  
 0.965
argE
Acetylornithine deacetylase; Similar to SP:P23908 GB:X55417 GB:X62807 PID:396304 PID:40955; identified by sequence similarity; putative; Belongs to the peptidase M20A family. ArgE subfamily.
  
 
 0.965
carA
Carbamoyl-phosphate synthase, small subunit; Similar to GB:D10483 SP:P00907 GB:J01597 PID:285764 PID:551790; identified by sequence similarity; putative; Belongs to the CarA family.
  
 
 0.959
pyrB
Aspartate carbamoyltransferase, catalytic subunit; Similar to PID:1708787; identified by sequence similarity; putative.
 
  
0.955
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
 
  
  0.955
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.